Erdmann W, Salt P J, Agoston S, Langrehr D
Acta Anaesthesiol Belg. 1979 Dec;30(4):239-45.
In healthy volunteers pretreated with atropine (0.5 mg), ketamine given as a bolus i.v. injection (2 mg/kg) followed by an infusion of ketamine (1 mg/kg/hr) for one hour, caused a significant rise in blood pressure and heart rate. This cardiovascular stimulation was rapidly counteracted by diazepam (0.2 mg/kg i.v.) given when the response to ketamine was already maximal.
在预先用阿托品（0.5毫克）处理过的健康志愿者中，静脉推注氯胺酮（2毫克/千克），随后以1毫克/千克/小时的速度输注氯胺酮1小时，导致血压和心率显著升高。当对氯胺酮的反应达到最大值时静脉注射地西泮（0.2毫克/千克），迅速抵消了这种心血管刺激作用。
