Samaan H A
Thorax. 1970 Nov;25(6):665-8. doi: 10.1136/thx.25.6.665.
In a series of 65 patients operated upon for ventricular septal defects (VSD), no mortality was attributed to pre-operative raised pulmonary vascular resistance. Eight patients with a severe degree of pulmonary vascular resistance made a full recovery after surgical closure of the ventricular septal defect. Three patients were cyanotic at the time of operation. Mortality in the series was the result of inadequate perfusion during operation, haemorrhage, cardiac tamponade, mediastinal infection, complete heart block or the development of post-operative aortic incompetence. Raised pulmonary vascular resistance and clinical evidence of a dominant left-to-right shunt in the absence of serious intracardiac anatomical complications does not contraindicate surgery for the repair of VSD.
在一系列65例因室间隔缺损（VSD）接受手术的患者中，没有死亡病例归因于术前肺血管阻力升高。8例肺血管阻力严重的患者在室间隔缺损手术闭合后完全康复。3例患者在手术时出现发绀。该系列中的死亡是手术期间灌注不足、出血、心脏压塞、纵隔感染、完全性心脏传导阻滞或术后主动脉瓣关闭不全发展的结果。在没有严重心内解剖并发症的情况下，肺血管阻力升高和明显左向右分流的临床证据并不构成VSD修复手术的禁忌证。
