Lavaud J, Besson-Leaud M, Prat J J, Receveur M, Cloup M
Ann Med Interne (Paris). 1979;130(11):569-76.
Endobronchial scraping was used in 53 immunodeficient children, aged 4 months to 15 years, and divided into three categories (37 receiving immunosuppression treatment, 8 with marasmus, and 8 with immunodeficiency), in order to determine the etiology of their interstitial pneumopathy. The examination was made under blind conditions in 21 cases using an intubation tube (under assisted ventilation), and with bronchoscopy under general anesthesia in the other 32 cases. Three scrapings were required for cytological, bacteriological, and virological and mycological examinations. In 32 cases (60%), the etiology of the interstitial pneumopathy was discovered; in 18 patients it was due to pneumocystis carinii, in 10 cases to bacterial infection, in 7 cases a viral infection, and in 3 others a fungal infection. An association of infective agents was reported in 6 cases. The major incident observed was a pneumothorax in 17% of the cases, more especially in 45% of the children under 20 months of age. Bronchial scraping is a valid examination the results and complications of which compare well with other non-vascular methods of diagnostic evaluation of such lesions.
对53名年龄在4个月至15岁的免疫缺陷儿童进行了支气管内刮片检查,这些儿童分为三类(37名接受免疫抑制治疗,8名患有消瘦症,8名患有免疫缺陷),以确定其间质性肺病的病因。21例在盲视条件下使用插管(在辅助通气下)进行检查,另外32例在全身麻醉下进行支气管镜检查。需要进行三次刮片以进行细胞学、细菌学、病毒学和真菌学检查。在32例(60%)中发现了间质性肺病的病因;18例是由于卡氏肺孢子虫,10例是由于细菌感染,7例是病毒感染,另外3例是真菌感染。6例报告了感染因子的联合感染。观察到的主要并发症是17%的病例发生气胸,特别是在20个月以下的儿童中占45%。支气管刮片是一种有效的检查方法,其结果和并发症与其他诊断此类病变的非血管性评估方法相比良好。