[正常受试者和原发性甲状腺功能减退症患者促甲状腺激素分泌的时间生物学特征]
[Chronobiological aspects of TSH secretion in control subjects and in subjects with primary hypothyroidism].
作者信息
Lattanzi V, Scardapane R, Santoro G, Mongelli S, Giorgino R
出版信息
Boll Soc Ital Biol Sper. 1979 Nov 30;55(22):2358-64.
PMID:549602
Abstract
The circadian rhythm in plasma TSH concentration was demonstrated in euthyroid subjects and in treated hypothyroid patients. Our results suggest that two hypothalamic areas, involved in TRH secretion, are responsables in basal as well impulsive pituitary TSH dismission.
摘要
在甲状腺功能正常的受试者和接受治疗的甲状腺功能减退患者中均证实了血浆促甲状腺激素（TSH）浓度的昼夜节律。我们的结果表明，参与促甲状腺激素释放激素（TRH）分泌的两个下丘脑区域，对垂体TSH的基础释放和脉冲式释放均有影响。
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