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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Fisher R B, Gilbert J C

J Physiol. 1970 Sep;210(2):287-95. doi: 10.1113/jphysiol.1970.sp009210.

The fractional permeation of heart cell water by L-arabinose and D-xylose after a standard period of perfusion is less the higher the extracellular pentose concentration.2. At any given pentose concentration the kinetics of permeation are consistent with passive diffusion through the cytoplasm or with transport across the cell membrane by a saturable carrier.3. The concentration dependence of permeation is inconsistent with passive diffusion.4. The kinetics of L-arabinose permeation are consistent with a carrier having V(max) = 2.2 m-mole/l. extracellular water per min and a half-saturation concentration [K] of 0.5 x 10(-4)M. The corresponding figures for D-xylose are V(max) = 1.4, [K] = 1.6 x 10(-4)M.

在标准灌注期后，细胞外戊糖浓度越高，L-阿拉伯糖和D-木糖对心脏细胞水的分数渗透率越低。2. 在任何给定的戊糖浓度下，渗透动力学与通过细胞质的被动扩散或通过可饱和载体跨细胞膜的转运一致。3. 渗透的浓度依赖性与被动扩散不一致。4. L-阿拉伯糖渗透的动力学与一个载体一致，该载体的V(max) = 2.2毫摩尔/升细胞外水每分钟，半饱和浓度[K]为0.5×10⁻⁴M。D-木糖的相应数值为V(max) = 1.4，[K] = 1.6×10⁻⁴M。

Fisher R B, Gilbert J C

J Physiol. 1970 Sep;210(2):287-95. doi: 10.1113/jphysiol.1970.sp009210.

The fractional permeation of heart cell water by L-arabinose and D-xylose after a standard period of perfusion is less the higher the extracellular pentose concentration.2. At any given pentose concentration the kinetics of permeation are consistent with passive diffusion through the cytoplasm or with transport across the cell membrane by a saturable carrier.3. The concentration dependence of permeation is inconsistent with passive diffusion.4. The kinetics of L-arabinose permeation are consistent with a carrier having V(max) = 2.2 m-mole/l. extracellular water per min and a half-saturation concentration [K] of 0.5 x 10(-4)M. The corresponding figures for D-xylose are V(max) = 1.4, [K] = 1.6 x 10(-4)M.

在标准灌注期后，细胞外戊糖浓度越高，L-阿拉伯糖和D-木糖对心脏细胞水的分数渗透率越低。2. 在任何给定的戊糖浓度下，渗透动力学与通过细胞质的被动扩散或通过可饱和载体跨细胞膜的转运一致。3. 渗透的浓度依赖性与被动扩散不一致。4. L-阿拉伯糖渗透的动力学与一个载体一致，该载体的V(max) = 2.2毫摩尔/升细胞外水每分钟，半饱和浓度[K]为0.5×10⁻⁴M。D-木糖的相应数值为V(max) = 1.4，[K] = 1.6×10⁻⁴M。