Gane N F, Lindup R, Strickland P, Bennett M H
Br J Cancer. 1970 Dec;24(4):705-11. doi: 10.1038/bjc.1970.84.
Six cases of fibrosarcoma arising in previously irradiated tissues are reported, out of a total of 220 cases of fibrosarcoma treated at Mount Vernon Hospital during the last 23 years.This rare occurrence may follow at any interval from 3 to 38 years after irradiation, usually after high dosage. Four of our six cases are known to have died of the disease.The literature regarding radiation-induced fibrosarcoma is reviewed and it is suggested that adequate excision or amputation may be curative, if undertaken early enough.
本文报告了6例发生于既往接受过放疗组织的纤维肉瘤病例,这6例病例来自于过去23年在弗农山医院接受治疗的220例纤维肉瘤患者。这种罕见情况可在放疗后3至38年的任何时间段出现,通常发生于高剂量放疗后。我们的6例病例中有4例已知死于该病。本文对辐射诱发纤维肉瘤的相关文献进行了综述,并提出如果能足够早地进行充分切除或截肢,可能治愈该病。