Graham J A, Scobie W G
Arch Dis Child. 1970 Aug;45(242):473-7. doi: 10.1136/adc.45.242.473.
Body water and electrolytes have been measured in normal infants and children using a muscle biopsy technique. Extracellular water, sodium, and chloride contents per kilogram dry weight are high in infancy but fall to adult values by 18 months to 2 years. Intracellular water and potassium contents are initially high, but approximate to adult levels around 6 months of age. Large variations in water and electrolyte contents have been found in apparently normal children. There is good correlation between extracellular water and sodium content, and between intracellular water and potassium content. Therefore intracellular electrolyte concentrations are similar for children of all ages. This technique is presented as a useful method of obtaining information about fluid and electrolyte balance in children.
采用肌肉活检技术对正常婴幼儿和儿童的体液及电解质进行了测量。每千克干重的细胞外液、钠和氯含量在婴儿期较高，但到18个月至2岁时降至成人水平。细胞内液和钾含量最初较高，但在6个月左右接近成人水平。在看似正常的儿童中发现了体液和电解质含量的巨大差异。细胞外液与钠含量之间以及细胞内液与钾含量之间存在良好的相关性。因此，各年龄段儿童的细胞内电解质浓度相似。该技术是获取儿童体液和电解质平衡信息的一种有用方法。
