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1
Comparison of serum growth hormone levels after Bovril and insulin stimulation.牛肉汁和胰岛素刺激后血清生长激素水平的比较。
Arch Dis Child. 1970 Aug;45(242):544-6. doi: 10.1136/adc.45.242.544.
2
The effect of arginine infusion on plasma growth hormone and insulin in children.精氨酸输注对儿童血浆生长激素和胰岛素的影响。
J Pediatr. 1969 Feb;74(2):187-97. doi: 10.1016/s0022-3476(69)80066-1.
3
A simple oral test of growth-hormone secretion in children.一种用于儿童生长激素分泌的简单口服测试。
Lancet. 1968 Aug 17;2(7564):373-5. doi: 10.1016/s0140-6736(68)90592-8.
4
The advantages of combined stimulation by arginine and insulin in the study of the secretion of growth hormone.精氨酸与胰岛素联合刺激在生长激素分泌研究中的优势。
Rev Eur Etud Clin Biol. 1972 Nov;17(9):846-54.
5
Blood glucose, serum insulin and growth hormone response to intravenous administration of arginine in premature infants.早产儿静脉注射精氨酸后的血糖、血清胰岛素及生长激素反应。
Biol Neonate. 1972;20(3):262-9. doi: 10.1159/000240470.
6
[Response of immunoreactive STH in children during simultaneous stimulation by arginine and insulin].[精氨酸和胰岛素同时刺激下儿童免疫反应性生长激素的反应]
Ann Endocrinol (Paris). 1970 Jan-Feb;31(1):144-52.
7
The significance of intermediate plasma growth hormone levels in growth-retarded children.生长发育迟缓儿童中等水平血浆生长激素的意义。
J Pediatr. 1972 Dec;81(6):1092-6. doi: 10.1016/s0022-3476(72)80237-3.
8
Radioimmunoassay of growth hormone in human plasma. Methodological studies and plasma immunoreactive growth hormone concentration during insulin induced hypoglycaemia in normal children and adults.人血浆中生长激素的放射免疫测定。正常儿童和成人胰岛素诱导低血糖期间的方法学研究及血浆免疫反应性生长激素浓度
Acta Endocrinol (Copenh). 1972 Dec;71(4):649-64.
9
Glucose and immunoreactive insulin disappearance from the circulation following intravenous insulin administration, and the growth hormone response.静脉注射胰岛素后循环中葡萄糖和免疫反应性胰岛素的消失情况,以及生长激素反应。
Clin Sci. 1969 Oct;37(2):371-80.
10
Normal growth with subnormal growth-hormone levels.生长激素水平低于正常的正常生长。
N Engl J Med. 1968 Sep 12;279(11):559-66. doi: 10.1056/NEJM196809122791101.

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Recessively inherited growth hormone deficiency in a family from Iraq.来自伊拉克的一个家族中的隐性遗传生长激素缺乏症。
J Med Genet. 1980 Aug;17(4):288-90. doi: 10.1136/jmg.17.4.288.
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Endocrine function, morbidity, and mortality after surgery for craniopharyngioma.颅咽管瘤手术后的内分泌功能、发病率和死亡率。
Arch Dis Child. 1982 Nov;57(11):837-41. doi: 10.1136/adc.57.11.837.
3
Effect of human growth hormone treatment for 1 to 7 years on growth of 100 children, with growth hormone deficiency, low birthweight, inherited smallness, Turner's syndrome, and other complaints.对100名患有生长激素缺乏症、低出生体重、遗传性身材矮小、特纳综合征及其他病症的儿童进行1至7年生长激素治疗的效果
Arch Dis Child. 1971 Dec;46(250):745-82. doi: 10.1136/adc.46.250.745.
4
Exercise as a screening test for growth hormone deficiency in children.运动作为儿童生长激素缺乏症的筛查测试。
Arch Dis Child. 1973 Jul;48(7):508-12. doi: 10.1136/adc.48.7.508.

本文引用的文献

1
PLASMA GROWTH HORMONE RESPONSE TO INTRAVENOUS ADMINISTRATION OF AMINO ACIDS.血浆生长激素对静脉注射氨基酸的反应。
J Clin Endocrinol Metab. 1965 Aug;25:1140-4. doi: 10.1210/jcem-25-8-1140.
2
A QUANTITATIVE STUDY OF ANTIGEN--ANTIBODY COMBINATION DURING DISK ELECTROPHORESIS IN ACRYLAMIDE GEL USING IODINE-131 LABELLED HUMAN GROWTH HORMONE.使用碘 - 131标记的人生长激素对丙烯酰胺凝胶盘状电泳过程中抗原 - 抗体结合的定量研究。
Immunology. 1964 May;7(3):307-15.
3
STUDIES ON THE SECRETION OF HUMAN-PITUITARY-GROWTH HORMONE.人类垂体生长激素分泌的研究
Br Med J. 1964 Mar 28;1(5386):804-7. doi: 10.1136/bmj.1.5386.804.
4
Hypoglycemia: a potent stimulus to secretion of growth hormone.低血糖:生长激素分泌的有力刺激因素。
Science. 1963 May 31;140(3570):987-8. doi: 10.1126/science.140.3570.987.
5
Studies of growth hormone secretion in children: normal, hypopituitary and constitutionally delayed.儿童生长激素分泌的研究:正常、垂体功能减退和体质性生长延迟。
J Clin Endocrinol Metab. 1967 Oct;27(10):1409-17. doi: 10.1210/jcem-27-10-1409.
6
Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. I.1965年英国儿童从出生到成年的身高、体重、身高增长速度和体重增长速度标准。I
Arch Dis Child. 1966 Oct;41(219):454-71. doi: 10.1136/adc.41.219.454.
7
The diurnal pattern of plasma growth hormone concentration in children and adolescents.儿童和青少年血浆生长激素浓度的昼夜模式。
J Endocrinol. 1966 Feb;34(2):147-53. doi: 10.1677/joe.0.0340147.
8
Growth and growth hormone. IV. Limitations of the growth hormone response to insulin and arginine and of the immunoreactive insulin response to arginine in the assessment of growth hormone deficiency in children.生长与生长激素。IV. 在评估儿童生长激素缺乏症时,生长激素对胰岛素和精氨酸反应的局限性以及免疫反应性胰岛素对精氨酸反应的局限性。
Pediatrics. 1969 Jun;43(6):989-1004.
9
Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen.使用带有非致癌显色剂的氧化酶-过氧化物酶系统测定血糖。
J Clin Pathol. 1969 Mar;22(2):158-61. doi: 10.1136/jcp.22.2.158.
10
The effect of age, sex and exercise on the secretion of growth hormone.年龄、性别和运动对生长激素分泌的影响。
Clin Sci. 1969 Dec;37(3):765-74.

牛肉汁和胰岛素刺激后血清生长激素水平的比较。

Comparison of serum growth hormone levels after Bovril and insulin stimulation.

作者信息

Grant D B, Jackson D, Raiti S, Clayton B E

出版信息

Arch Dis Child. 1970 Aug;45(242):544-6. doi: 10.1136/adc.45.242.544.

DOI:10.1136/adc.45.242.544
PMID:5506941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1647626/
Abstract

Serum growth hormone (HGH) levels were estimated in 60 children during Bovril and intravenous insulin tests. The results of the two tests correlated well. 37 subjects had HGH levels over 10 μIU/ml. during both tests, and 18 subjects failed to respond to either test. 4 subjects showed minor discrepancies between the results of the two tests, and one child with the emotional deprivation syndrome had a good response to insulin but no significant rise in serum HGH during her first Bovril test. It was concluded that the two tests were of comparable value in the assessment of children with suspected growth hormone deficiency, and that the Bovril test had the advantages of being safe and avoiding intravenous administration.

摘要

在60名儿童进行牛肉汁试验和静脉注射胰岛素试验期间,对其血清生长激素(HGH)水平进行了评估。两项试验结果相关性良好。37名受试者在两项试验中HGH水平均超过10μIU/ml,18名受试者对两项试验均无反应。4名受试者两项试验结果存在轻微差异,一名患有情感剥夺综合征的儿童对胰岛素反应良好,但在首次牛肉汁试验期间血清HGH未显著升高。得出的结论是,在评估疑似生长激素缺乏的儿童时,这两项试验具有相当的价值,并且牛肉汁试验具有安全且无需静脉给药的优点。