Grant D B, Jackson D, Raiti S, Clayton B E
Arch Dis Child. 1970 Aug;45(242):544-6. doi: 10.1136/adc.45.242.544.
Serum growth hormone (HGH) levels were estimated in 60 children during Bovril and intravenous insulin tests. The results of the two tests correlated well. 37 subjects had HGH levels over 10 μIU/ml. during both tests, and 18 subjects failed to respond to either test. 4 subjects showed minor discrepancies between the results of the two tests, and one child with the emotional deprivation syndrome had a good response to insulin but no significant rise in serum HGH during her first Bovril test. It was concluded that the two tests were of comparable value in the assessment of children with suspected growth hormone deficiency, and that the Bovril test had the advantages of being safe and avoiding intravenous administration.
在60名儿童进行牛肉汁试验和静脉注射胰岛素试验期间,对其血清生长激素(HGH)水平进行了评估。两项试验结果相关性良好。37名受试者在两项试验中HGH水平均超过10μIU/ml,18名受试者对两项试验均无反应。4名受试者两项试验结果存在轻微差异,一名患有情感剥夺综合征的儿童对胰岛素反应良好,但在首次牛肉汁试验期间血清HGH未显著升高。得出的结论是,在评估疑似生长激素缺乏的儿童时,这两项试验具有相当的价值,并且牛肉汁试验具有安全且无需静脉给药的优点。