Benzpyrene pretreatment changes the kinetics and pH optimum for aniline hydroxylation in vitro, but not those for benzphetamine demethylation in vitro by rat liver microsomes.
作者信息
Rickert D E, Fouts J R
出版信息
Biochem Pharmacol. 1970 Feb;19(2):381-90. doi: 10.1016/0006-2952(70)90193-0.
PMID:5507656
Abstract
摘要
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Effect of repeated exposure to aniline, nitrobenzene, and benzene on liver microsomal metabolism in the rat.反复接触苯胺、硝基苯和苯对大鼠肝脏微粒体代谢的影响。
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