Lograno M D, Siro-Brigiani G, Cortese I
Boll Soc Ital Biol Sper. 1979 Apr 15;55(7):682-8.
Lidocaine, mepivacaine and prilocaine cause in rats an increase of the frequency of the spontaneous contractions and an increase of the tone on the detrusor muscle of the urinary bladder. These effects are not antagonized by atropine and by fentola mine. On the contrary verapamil and papaverine antagonize these above effects.