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口服雌三醇对播散性前列腺癌的姑息治疗

Palliative treatment with oral Estracyte in disseminated prostatic carcinoma.

作者信息

Welvaart K

出版信息

Arch Chir Neerl. 1975;27(3):193-8.

PMID:55103
Abstract

In Roswell Park Memorial Institute, between 1969 and 1974, a total of 32 patients with widespread metastasized carcinoma of the prostate were treated with oral Estracyt. Objectively demonstrable remissions were achieved in eight patients (8/32 equals 25%). Subjective improvement of their general condition was experienced by 15 patients (15/32 equals 47%). The toxicity of Estracyt manifests itself with gastrointestinal disorders, which in most cases are amenable to anti-emetic treatment.

摘要

1969年至1974年间,在罗斯韦尔帕克纪念研究所,共有32例广泛转移的前列腺癌患者接受了口服癌腺治治疗。8例患者(8/32,即25%)实现了客观可证实的缓解。15例患者(15/32,即47%)感觉全身状况有主观改善。癌腺治的毒性表现为胃肠道紊乱,大多数情况下可通过止吐治疗来缓解。

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