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口服雌三醇对播散性前列腺癌的姑息治疗

Palliative treatment with oral Estracyte in disseminated prostatic carcinoma.

作者信息

Welvaart K

出版信息

Arch Chir Neerl. 1975;27(3):193-8.

PMID:55103
Abstract

In Roswell Park Memorial Institute, between 1969 and 1974, a total of 32 patients with widespread metastasized carcinoma of the prostate were treated with oral Estracyt. Objectively demonstrable remissions were achieved in eight patients (8/32 equals 25%). Subjective improvement of their general condition was experienced by 15 patients (15/32 equals 47%). The toxicity of Estracyt manifests itself with gastrointestinal disorders, which in most cases are amenable to anti-emetic treatment.

摘要

1969年至1974年间,在罗斯韦尔帕克纪念研究所,共有32例广泛转移的前列腺癌患者接受了口服癌腺治治疗。8例患者(8/32,即25%)实现了客观可证实的缓解。15例患者(15/32,即47%)感觉全身状况有主观改善。癌腺治的毒性表现为胃肠道紊乱,大多数情况下可通过止吐治疗来缓解。

相似文献

1
Palliative treatment with oral Estracyte in disseminated prostatic carcinoma.口服雌三醇对播散性前列腺癌的姑息治疗
Arch Chir Neerl. 1975;27(3):193-8.
2
[Clinical effects of estramustine phosphate disodium (Estracyt) on prostatic cancer].
Hinyokika Kiyo. 1986 Nov;32(11):1763-70.
3
Continuous versus intermittent oral therapy with estramustine phosphate (Estracyt).磷酸雌莫司汀(癌腺治)的持续口服治疗与间歇口服治疗对比
Scand J Urol Nephrol Suppl. 1980;55:147-9.
4
[Estracyt treatment in prostatic neoplasms].[雌氮芥治疗前列腺肿瘤]
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5
[The phase IV studies with Estracyt in prostatic cancer].
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Treatment of advanced carcinoma of the prostate with Estracyt.用癌腺治(Estracyt)治疗晚期前列腺癌。
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[Serum testosterone and acid phosphatase levels in patients with prostatic cancer treated with Estracyt].[接受雌氮芥治疗的前列腺癌患者的血清睾酮和酸性磷酸酶水平]
Orv Hetil. 1981 Apr 26;122(17):1017-20.
8
New steroidal alkylating agents in advanced stage D carcinoma of the prostate.
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[Total remission of prostatic cancer following treatment with Estracyt].[使用依西美坦治疗后前列腺癌完全缓解]
Orv Hetil. 1982 Jan 31;123(5):287-9.
10
[Treatment of advanced carcinoma of the prostate with estramustine phosphate (estracyt)].磷酸雌莫司汀(癌腺治)治疗晚期前列腺癌
Actas Urol Esp. 1984 Sep-Oct;8(5):399-402.