Jung H, Gamm H, Eissner D
Arch Otorhinolaryngol. 1975 Nov 30;211(2):129-38. doi: 10.1007/BF01221120.
Tumorscanning of malignomas and their metastatic nodules in head and neck is an enrichment of diagnostic possibilities. For the examination such substances can be used, which are tumoraffine and well to mark with a radio-isotope. Therefore we have marked the cytostatic drug Bleomycine with 57Co. Scans were performed with the Anger-Camera 4 to 6 hrs after intravenous injection of 1 mCi 57Co-Bleomycine. 60 patients with different malignomas have been examined, 46 with tumor-localization in head and neck, the others in thoraxabdomen. 34 (85%) of the head and neck malignomas could be demonstrated; 21 (81%) were squamous cell carcinomas, 13 (69%) sarcomas. The possibilities of this method are shown; its clinical importance lies in the identification of primary tumors and their metastatic nodules, of relapses and tumorrests as well as the localization of distant metastasises.
对头颈部恶性肿瘤及其转移结节进行肿瘤扫描可增加诊断的可能性。对于该项检查,可使用对肿瘤有亲和力且易于用放射性同位素标记的物质。因此,我们用57钴标记了细胞抑制药物博来霉素。静脉注射1毫居里57钴 - 博来霉素后4至6小时,使用安格相机进行扫描。对60例患有不同恶性肿瘤的患者进行了检查,其中46例肿瘤位于头颈部,其他患者的肿瘤位于胸腹部位。头颈部恶性肿瘤中有34例(85%)能够被显示出来;其中21例(81%)为鳞状细胞癌,13例(69%)为肉瘤。展示了该方法的可行性;其临床重要性在于识别原发性肿瘤及其转移结节、复发灶和肿瘤残留,以及远处转移灶的定位。