Verstraeten J M
Rev Inst Hyg Mines (Hasselt). 1978;33(4):200-3.
In a single blind cross-over study 12 patients with asthma received in randomised order aerosols of pirbuterol 400 micrograms, salbutamol 200 micrograms or placebo. Only 9 patients met the criteria and were taken into account for the statistical analysis, namely a stable reversible broncho-obstruction. Pirbuterol and salbutamol did induce a considerable bronchodilation. Both drugs had a similar activity and few side effects.
在一项单盲交叉研究中,12名哮喘患者以随机顺序接受了400微克吡布特罗气雾剂、200微克沙丁胺醇气雾剂或安慰剂。只有9名患者符合标准并被纳入统计分析,即稳定的可逆性支气管阻塞。吡布特罗和沙丁胺醇确实引起了显著的支气管扩张。两种药物活性相似,副作用较少。