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[美替异戊醇治疗传染性肝炎的评估。阴性结果]

[Evaluation of methisoprinol+ in the treatment of infectious hepatitis. Negative results].

作者信息

Sánchez R, Chena M, Serafín F, Ruiz-Gómez J, Trucíos G, Gutiérrez G

出版信息

Bol Med Hosp Infant Mex. 1976 Jan-Feb;33(1):203-11.

PMID:55267
Abstract

The usefulness of metisoprinol was evaluated by a double blind study and at random in the treatment of mild infectious hepatitis in a group of 42 children. Twenty-one patients were given the drug at the dose of 50 mg/kg/day, divided t.i.d., by mouth and for 12 days. The other twenty-one patients made up the control group and were given placebo. No modifications nor clinical differences were found in the parameters evaluated; laboratory results were also negative in the studies carried out that might be attributed to the administration of the drug.

摘要

通过双盲随机研究评估了美替索诺尔对42名儿童轻度传染性肝炎的治疗效果。21名患者按50mg/kg/天的剂量口服给药,每日三次,共12天。另外21名患者组成对照组,给予安慰剂。在评估的参数中未发现任何变化或临床差异;所进行的研究中的实验室结果也为阴性,可能与药物给药有关。

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