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[肝素及一种人肝素可沉淀血浆组分对体外抗体产生细胞的作用]

[The effect of heparin and a human heparin precipitable plasma fraction on antibody producing cells in vitro].

作者信息

Kaznacheev S V, Kozlov V A, Petrova E M, Lozovoĭ V P

出版信息

Biull Eksp Biol Med. 1976 Jan;81(1):57-9.

PMID:55280
Abstract

A study was made of the effect of heparin and heparin-precipitable fractions of human blood plasms (HPF) on the capacity of the cells of mouse spleen immunized with sheep erythrocytes to plaque-formation in vitro. It was found that heparin and HPF produced an inhibitory effect on the reaction of plaque formation as a result of interaction with lymphocytes. It is supposed that a possible point of application of heparin and HPF action are surface cell membranes of the antibody-forming cells.

摘要

研究了肝素及人血浆中可被肝素沉淀的组分(HPF)对用绵羊红细胞免疫的小鼠脾脏细胞在体外形成噬斑能力的影响。发现肝素和HPF与淋巴细胞相互作用,对噬斑形成反应产生抑制作用。推测肝素和HPF作用的一个可能作用点是抗体形成细胞的表面细胞膜。

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