芳香族氨基酸脱羧酶抑制对人体催乳素分泌的影响。
Effects of the inhibition of aromatic aminoacids decarboxylase on prolactin secretion in humans.
作者信息
Masturzo P, Murialdo G, Carolei A, Polleri A
出版信息
Boll Soc Ital Biol Sper. 1979 Feb 28;55(4):366-72.
PMID:552852
Abstract
Carbidopa, at the dose of 250 mg. and benserazide at the dose of 125 mg, given orally in a single dose to healthy women aged between 23 - 26 years enhance significantly serum prolactin. The effect is not shared by two other inhibitors of AADC, namely alpha-methyl DOPA (500 mg) and fentiazac (400 mg). The effect of benserazide is suppressed by bromocriptine (2.5 mg) and blunted by 1-DOPA (400 mg) given orally simultaneusly.
摘要
卡比多巴（剂量为250毫克）和苄丝肼（剂量为125毫克），单次口服给予年龄在23至26岁的健康女性后，可显著提高血清催乳素水平。另外两种芳香氨基酸脱羧酶抑制剂，即α-甲基多巴（500毫克）和芬替酸（400毫克）则无此作用。苄丝肼的这种作用可被口服的溴隐亭（2.5毫克）抑制，并被左旋多巴（400毫克）同时口服减弱。
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