Barrett T W
Cancer Biochem Biophys. 1979;3(4):189-92.
The theory of cancer induction of ultimate carcinogens by parametric excitation is presented. Attention is drawn to the requirement of an energy transfer in perturbing DNA. The concept of energy transfer by resonance is rejected in favor of energy transfer by parametric excitation of which resonance is a special case. The result, reported here, is a remarkable agreement between the Raman vibrational bands of these ultimate carcinogens, various hypochromic bands of DNA and the predictions of parametric excitation theory. This result suggests that the peculiar relation of an ultimate carcinogen and DNA results in parametrically induced energy transfer in the vibrational mode. The problem, then, of cancer induction becomes one of analytical mechanics.
提出了通过参量激发诱导癌症的理论。人们注意到在干扰DNA时能量转移的必要性。共振能量转移的概念被摒弃,转而支持参量激发的能量转移,而共振是参量激发的一种特殊情况。此处报道的结果是,这些最终致癌物的拉曼振动带、DNA的各种减色带与参量激发理论的预测之间存在显著的一致性。这一结果表明,最终致癌物与DNA之间的特殊关系导致了振动模式下参量诱导的能量转移。因此,癌症诱导问题就变成了一个分析力学问题。