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海洋鱼类肝脏中混合功能氧化酶活性与超微结构变化的相关性

Correlation of mixed-function oxidase activity with ultrastructural changes in the liver of a marine fish.

作者信息

Schoor W P, Couch J A

出版信息

Cancer Biochem Biophys. 1979;4(2):95-103.

PMID:552910
Abstract

Specimens of mullet (Mugil cephalus), a marine fish, were given single doses of 3-methylcholanthrene intraperitoneally and the activity of the microsomal mixed-function oxygenase system in the liver was measured by the metabolism of benzo(a)pyrene. The enzyme system was found to be inducible with concomitant ultrastructural changes in the hepatocytes. The specific activity and the metabolic profile approximate those of the rat.

摘要

选取海洋鱼类鲻鱼( Mugil cephalus )的样本,给它们腹腔注射单剂量的3-甲基胆蒽,然后通过苯并(a)芘的代谢来测定肝脏中微粒体混合功能氧化酶系统的活性。结果发现该酶系统是可诱导的,同时肝细胞出现超微结构变化。其比活性和代谢特征与大鼠的相近。

相似文献

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Correlation of mixed-function oxidase activity with ultrastructural changes in the liver of a marine fish.海洋鱼类肝脏中混合功能氧化酶活性与超微结构变化的相关性
Cancer Biochem Biophys. 1979;4(2):95-103.
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Hepatic microsomal mixed-function oxidase activity of several marine species from coastal Maine.缅因州沿海几种海洋物种的肝脏微粒体混合功能氧化酶活性。
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