Eastham R D
J Clin Pathol. 1970 Jul;23(5):407-10. doi: 10.1136/jcp.23.5.407.
It has been found that adhesive platelet counts are not of clinical use either after surgical operation or during long-term anticoagulant therapy in the detection of thrombosis. Calculation of the theoretical risk of development of platelet thrombi related to the platelet count suggests a possible reason for this absence of clinical significance. The evidence that platelet adhesiveness alters because of uncontrollable platelet variables and is controlled at least in part by plasma factors is discussed. The possibility of measuring the plasma factors is considered briefly.
已经发现，在外科手术后或长期抗凝治疗期间，粘附血小板计数在检测血栓形成方面并无临床用途。计算与血小板计数相关的血小板血栓形成的理论风险提示了这种缺乏临床意义的可能原因。文中讨论了血小板粘附性因无法控制的血小板变量而改变且至少部分受血浆因子控制的证据。简要考虑了测量血浆因子的可能性。
