Phillips I
Ann Ist Super Sanita. 1979;15(1):115-22.
Antibiotic sensitivity tests on most anaerobic organisms isolated from a given patient are seldom of use to that individual. This is because both isolation and sensitivity testing of this group of bacteria take so long. It is thus vital that the microbiologist should be able to supply to the clinician the cumulated results of past experience, ideally his own, but if not, then the experience of others, taking into account geographical variations whenever possible. Because of the possibility of geographical variation, it is important that every institution should carry out sensitivity testing on easily isolated and rapidly growing bacteria. Bacteroides fragilis is probably the most common of these, and because it is among the more resistant anaerobes and is present in the majority of anaerobic infections, it is often used as an "indicator" both of the diagnosis and of the likely response to a given drug regimen.
对从特定患者身上分离出的大多数厌氧生物进行抗生素敏感性测试，对该个体而言很少有用。这是因为这类细菌的分离和敏感性测试耗时都很长。因此，微生物学家必须能够向临床医生提供过去经验的累积结果，理想情况下是其自身的经验，但如果无法提供自身经验，那么也要提供其他人的经验，并尽可能考虑地域差异。由于存在地域差异的可能性，每个机构对易于分离和快速生长的细菌进行敏感性测试很重要。脆弱拟杆菌可能是其中最常见的，并且由于它是较耐药的厌氧菌之一，且存在于大多数厌氧感染中，它常被用作诊断以及对特定药物治疗方案可能反应的“指示菌”。
