Speranza V, Mennini G
Ann Ist Super Sanita. 1979;15(1):53-63.
In the past few years the incidence of anaerobes in the aetiology of surgical infections has definitely increased due to a distinct increase in anaerobic flora and to the noticeable improvement in isolation and culture techniques which have drastically decreased the incidence of so-called "sterile pus". The development of the toxi-infective shock due to Gram negative anaerobes, presents the most serious clinical problems, being the shock with the highest mortality rate. A paradigmatic example of shock due to surgical infections is the shock complicating peritonitis. A correct postoperative behaviour includes peritoneal lavage through drainages placed during surgery. The AA. personal experience with 50 hospitalized patients treated surgically and with cefoxitin, a new cephamycin semisynthetic antibiotic resistant to beta-lactamases, is reported.
在过去几年中,由于厌氧菌群明显增加以及分离和培养技术显著改进(这大幅降低了所谓“无菌性脓液”的发生率),厌氧菌在外科感染病因中的发生率确实有所上升。革兰氏阴性厌氧菌引起的毒感染性休克是最严重的临床问题,其死亡率最高。外科感染所致休克的一个典型例子是并发腹膜炎的休克。正确的术后处理包括通过手术中放置的引流管进行腹腔灌洗。本文报告了作者对50例接受手术治疗并使用头孢西丁(一种对β-内酰胺酶有抗性的新型半合成头孢霉素抗生素)的住院患者的个人经验。