Tarzia G, Panzone G, Schiatti P, Selva D
Farmaco Sci. 1979 Apr;34(4):316-30.
The unequivocal synthesis of some terms belonging to the two isomeric classes of the pyrrolo(1H,3H)[3,4-d]pyrimidin-2-ones and of the pyrrolo(1H,6H)[3,4-d]pyrimidin-2-ones is reported. Some of these compounds are active in inhibiting the development of the carrageenin edema, of the granuloma cotton pellet and of the adjuvant arthritis in the rat when administered orally.
据报道，已明确合成了属于吡咯并(1H,3H)[3,4-d]嘧啶-2-酮和吡咯并(1H,6H)[3,4-d]嘧啶-2-酮这两个异构类别的某些化合物。其中一些化合物经口服给药后，在抑制大鼠角叉菜胶性水肿、棉球肉芽肿和佐剂性关节炎的发展方面具有活性。
