Marini C, Molinaro G C, Capaldi M T, Giuliani F
G Batteriol Virol Immunol. 1979 Jan-Jun;72(1-6):160-8.
285 sera from parturient patients have been tested for the presence of anti-toxoplasma antibodies by the direct Agglutination test and for Immunoglobulins by the immunochemical turbidimetric determination. 17 sera showed a significant increase in the titre of anti-toxoplasma antibodies; 5 of these 17 presented a simultaneous IgM level increase, subsequently confirmed by a 2 Mercaptoethanol pretreatment, this fact suggesting the presence of active infectious disease. The authors think it can be useful in the diagnostic assessment of active toxoplasmic infectious disease the simultaneous screening of sera by the two described methods: the direct Agglutination test and the immunochemical turbidimetric determination.
通过直接凝集试验检测了285份产妇血清中抗弓形虫抗体的存在,并通过免疫化学比浊法测定了免疫球蛋白。17份血清显示抗弓形虫抗体滴度显著升高;这17份中的5份同时出现IgM水平升高,随后经2-巯基乙醇预处理得到证实,这一事实表明存在活动性传染病。作者认为,通过直接凝集试验和免疫化学比浊法这两种所述方法同时筛查血清,可能有助于活动性弓形虫传染病的诊断评估。