["低三碘甲状腺原氨酸（T3）综合征”：甲状腺素（T4）正常甲状腺功能的证据（作者译）]
["Low triiodothyronine (T3) syndrome": "thyroxine (T4) euthyroidism" evidence (author's transl)].
作者信息
Wémeau J L, Lefebvre J, Linquette M
出版信息
Nouv Presse Med. 1979 Feb 3;8(6):415-9.
PMID:554102
Abstract
As first described in serious systemic illnesses isolated decreased T3 plasma concentration was related to impaired peripheral conversion of T4, to T3 with preferential production of reverse T3 (rT3). A "low T3 syndrome" was seen in 47 out of 109 patients with extra-thyroidal diseases. Metabolic state, TSH and TSH responses to TRH were normal despite of low T3 concentration. Euthyroidism seems mainly due to T4 itself in these patients.
摘要
正如首次在严重全身性疾病中所描述的那样，孤立的血浆T3浓度降低与T4向T3的外周转化受损以及反向T3（rT3）的优先产生有关。109例甲状腺外疾病患者中有47例出现“低T3综合征”。尽管T3浓度较低，但代谢状态、促甲状腺激素（TSH）以及TSH对促甲状腺激素释放激素（TRH）的反应均正常。在这些患者中，甲状腺功能正常似乎主要归因于T4本身。
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