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Formation and significance of 6-methylthiopurine ribonucleotide as a metabolite of 6-mercaptopurine.

作者信息

Bennett L L, Allan P W

出版信息

Cancer Res. 1971 Feb;31(2):152-8.

PMID:5545266
Abstract
摘要

相似文献

1
Formation and significance of 6-methylthiopurine ribonucleotide as a metabolite of 6-mercaptopurine.
Cancer Res. 1971 Feb;31(2):152-8.
2
Metabolic studies with carbocyclic analogs of purine nucleosides.
Mol Pharmacol. 1968 May;4(3):208-17.
3
Feedback inhibition of purine biosynthesis in adenocarcinoma 755 and sarcoma 180 cells in culture.培养的腺癌细胞755和肉瘤180细胞中嘌呤生物合成的反馈抑制作用。
J Natl Cancer Inst. 1970 Oct;45(4):681-5.
4
[Formate activation and de novo synthesis of purine nucleotides in leukemia cells and its therapeutic modification by 6-mercaptopurine].[白血病细胞中嘌呤核苷酸的甲酸盐激活与从头合成及其6-巯基嘌呤的治疗性修饰]
Z Gesamte Exp Med Einschl Exp Chir. 1968;147(2):154-72.
5
[Participation of serine and histidine in formation of purine bases of nucleotides and nucleic acids in hepatoma].
Biokhimiia. 1967 Jul-Aug;32(4):746-50.
6
Synergistic effect of 6-mercaptopurine and 6-methylmercaptopurine ribonucleoside on the levels of adenine nucleotides of Sarcoma 180 cells.
Cancer Res. 1972 Feb;32(2):259-69.
7
Antitumor activity of 5-formamido-1- D-ribofuranosylthioimidazole-4-carboxamide 2',3',5'-triformate in a variety of animal tumors.5-甲酰胺基-1-D-呋喃核糖硫代咪唑-4-甲酰胺2',3',5'-三甲酸酯在多种动物肿瘤中的抗肿瘤活性
Cancer Chemother Rep. 1971 Jun;55(3):229-31.
8
Arabinosyl-6-mercaptopurine and arabinosyl-6-mercaptopurine-5'-phosphate: comparison of their metabolic effects.阿糖胞苷-6-巯基嘌呤和阿糖胞苷-6-巯基嘌呤-5'-磷酸：它们代谢作用的比较
Proc Soc Exp Biol Med. 1969 Jul;131(3):1038-41. doi: 10.3181/00379727-131-34035.
9
Mechanism of the growth inhibition potentiation arising from combination of 6-mercaptopurine with 6-(methylmercapto)purine ribonucleoside.6-巯基嘌呤与6-（甲基巯基）嘌呤核糖核苷联合使用产生生长抑制增强作用的机制。
Cancer Res. 1970 Sep;30(9):2379-87.
10
Decreased feedback inhibition in a 6-(methylmercapto)purine ribonucleoside-resistant tumor.6-（甲硫基）嘌呤核糖核苷抗性肿瘤中反馈抑制的降低
Cancer Res. 1967 Oct;27(10):1773-8.

引用本文的文献

1
IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations.硫唑嘌呤治疗的炎症性肠病患者的肌苷-5'-单磷酸脱氢酶活性——与硫嘌呤甲基转移酶活性及代谢物浓度的关系
Br J Clin Pharmacol. 2008 Jan;65(1):69-77. doi: 10.1111/j.1365-2125.2007.02985.x. Epub 2007 Jul 27.
2
Pharmacologically active metabolites of drugs and other foreign compounds. Clinical, pharmacological, therapeutic and toxicological considerations.药物及其他外来化合物的药理活性代谢产物。临床、药理、治疗及毒理学考量。
Drugs. 1982 Dec;24(6):519-42. doi: 10.2165/00003495-198224060-00003.
3
The clinical pharmacology of 6-mercaptopurine.
6-巯基嘌呤的临床药理学。
Eur J Clin Pharmacol. 1992;43(4):329-39. doi: 10.1007/BF02220605.
4
In vivo cytogenetic investigations in bone marrow cells of rats, Chinese hamsters and mice treated with 6-mercaptopurine.
Arch Toxicol. 1975;33(3):209-24. doi: 10.1007/BF00311274.