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经宫腔内注入前列腺素进行治疗性流产。

Therapeutic abortion by intrauterine instillation of prostaglandins.

作者信息

Embrey M P, Hillier K

出版信息

Br Med J. 1971 Mar 13;1(5749):588-90. doi: 10.1136/bmj.1.5749.588.

Abstract

In a preliminary study of 15 patients the clinical effectiveness of prostaglandins (PGE2 and PGF2alpha) as abortifacients when administered by intrauterine instillation compared favourably with previous studies using the intravenous route.Abortion was successfully induced in 14 patients. The average total dose of prostaglandins required was about one-third of the amount needed intravenously, and side effects were minimal.

摘要

在一项对15名患者的初步研究中,通过宫内滴注给予前列腺素(PGE2和PGF2α)作为堕胎药的临床效果与先前使用静脉途径的研究相比更具优势。14名患者成功引产。所需前列腺素的平均总剂量约为静脉注射所需量的三分之一,且副作用极小。

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本文引用的文献

1
The effect of prostaglandins on the human pregnant uterus.前列腺素对人类妊娠子宫的影响。
J Obstet Gynaecol Br Commonw. 1969 Sep;76(9):783-9. doi: 10.1111/j.1471-0528.1969.tb06178.x.
2
Induction of labour with prostaglandins E1 and E2.使用前列腺素E1和E2引产。
Br Med J. 1970 May 2;2(5704):256-8. doi: 10.1136/bmj.2.5704.256.
3
Induction of labour with prostaglandin E2.使用前列腺素E2引产。
J Obstet Gynaecol Br Commonw. 1970 Mar;77(3):200-10. doi: 10.1111/j.1471-0528.1970.tb03507.x.
4
The induction of labour with prostaglandin E2.
J Obstet Gynaecol Br Commonw. 1970 Mar;77(3):193-9. doi: 10.1111/j.1471-0528.1970.tb03506.x.
5
Use of prostaglandin E2 for therapeutic abortion.使用前列腺素E2进行治疗性流产。
Br Med J. 1970 Jul 25;3(5716):198-200. doi: 10.1136/bmj.3.5716.198.
6
Therapeutic abortion by local administration of prostaglandin.
Lancet. 1970 Oct 3;2(7675):716-7. doi: 10.1016/s0140-6736(70)91978-1.
7
Therapeutic abortion using prostaglandin F2alpha.
Lancet. 1970 Jan 24;1(7639):157-9. doi: 10.1016/s0140-6736(70)90402-2.

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