Embrey M P, Hillier K
Br Med J. 1971 Mar 13;1(5749):588-90. doi: 10.1136/bmj.1.5749.588.
In a preliminary study of 15 patients the clinical effectiveness of prostaglandins (PGE2 and PGF2alpha) as abortifacients when administered by intrauterine instillation compared favourably with previous studies using the intravenous route.Abortion was successfully induced in 14 patients. The average total dose of prostaglandins required was about one-third of the amount needed intravenously, and side effects were minimal.
在一项对15名患者的初步研究中,通过宫内滴注给予前列腺素(PGE2和PGF2α)作为堕胎药的临床效果与先前使用静脉途径的研究相比更具优势。14名患者成功引产。所需前列腺素的平均总剂量约为静脉注射所需量的三分之一,且副作用极小。