Szpirer C
Immunology. 1971 Feb;20(2):137-49.
The cysteine-containing peptides from the Fd′ fragments and the light chains of rabbit non-specific IgG and anti-tobacco mosaic virus (TMV) antibody have been compared by a peptide mapping technique allowing the detection of peptides present in very small quantities. Peptide maps of homologous fragments or chains are indistinguishable. However a fraction of anti-TMV antibody has been isolated which yields an Fd′ fragment showing some peptides not seen in the maps of other Fd′ fragments. We conclude that the rabbit anti-TMV antibody is structurally heterogeneous and the nature of this heterogeneity is discussed.
通过一种能够检测极少量肽段的肽图分析技术，对来自兔非特异性IgG和抗烟草花叶病毒（TMV）抗体的Fd′片段及轻链中的含半胱氨酸肽段进行了比较。同源片段或链的肽图无法区分。然而，已分离出一部分抗TMV抗体，其产生的Fd′片段显示出一些在其他Fd′片段的肽图中未出现的肽段。我们得出结论，兔抗TMV抗体在结构上是异质性的，并对这种异质性的性质进行了讨论。
