Neundörfer B, Kayser-Gatchalian C, Huber W, Werner W
J Neurol. 1976 Feb 13;211(3):263-74. doi: 10.1007/BF00313236.
80 strictly selected patients with chronic renal insufficiency with plasma creatinine values of 1.4-14.5 mg% were examined for clinical and electrophysiological signs of nephrogenic polyneuropathy. The motor symptoms complained of were cramps in 43.8% of the patients, "restless leggs" in 18.7%, muscular twitchings in 12.5%. It was emphasized that the first two symptoms do not always indicate the presence of polyneuropathy. 30% complained of paresthesias, 5% of "burning feet". The most frequent clinical finding was the impairment of vibration sense in the feet in 37.5% followed by diminshed appreciation of passive movement of the toes in 30%, weakening or absence of the ankle jerk in 23.8% and finally, weakening of the patellar reflex in 5%...
对80例严格挑选的慢性肾功能不全患者进行了检查，这些患者的血浆肌酐值为1.4 - 14.5mg%，以观察肾源性多发性神经病的临床和电生理体征。主诉的运动症状中，43.8%的患者有痉挛，18.7%有“不宁腿”，12.5%有肌肉抽搐。需要强调的是，前两种症状并不总是表明存在多发性神经病。30%的患者主诉感觉异常，5%主诉“足部烧灼感”。最常见的临床发现是37.5%的患者足部振动觉受损，其次是30%的患者对脚趾被动运动的感知减弱，23.8%的患者踝关节反射减弱或消失，最后是5%的患者髌反射减弱……
