Diagnostic procedures in sarcoidosis.

One hundred consecutive patients suspected of having sarcoidosis were examined by means of available diagnostic procedures and the results of the examinations were compared. While Kveim tests and/or lymphocyte transformation tests gave the most significant results in cases of less than two years' standing, a combination of these and organ biopsies is required for the diagnosis of cases of more than two years' duration.An interpretation of the immunological deviations observed in sarcoidosis is attempted on the basis of observations made on leukocyte cultures and on isolations of mycobacteriophages from patients with sarcoidosis.