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[血浆铁蛋白测定在缺铁筛查中的作用。关于对两组不同社会经济背景儿童的一项研究]

[The role of plasma ferritin determination in screening for iron deficiency. Apropos of a study in 2 groups of children of different socioeconomic background].

作者信息

Blot I, Tchernia G, Plimare C M, Courtecuisse V

出版信息

Arch Fr Pediatr. 1979 Nov;36(9):911-21.

PMID:555313
Abstract

A study of 72 children, aged between 6 and 24 months who came from socio-economic background has shown: plasma ferritin levels decrease gradually between 3 weeks and 6 months of age. Between 6 months and two years, levels reach a plateau but the values are lower than those of adults. The mean ferritin level is lower at any given age in children with iron deficiency but plasma ferritin levels may be in the normal range although there is obvious iron deficiency. By contrast the saturation of siderophillin can be used to determine inadequate supplies of iron to the marrow. The frequency of iron dificiency in infants under 1 year was similar in the two socio-economic groups. However between 1 and 2 years no iron deficiency was detected in the children under regular supervision but all the infants who were socially disadvantaged became iron-deficient demonstrating the need for regular iron supplements.

摘要

一项针对72名年龄在6至24个月、来自社会经济背景各异家庭的儿童的研究表明:血浆铁蛋白水平在3周龄至6月龄之间逐渐下降。在6个月至2岁之间,水平达到平稳状态,但数值低于成年人。缺铁儿童在任何给定年龄的平均铁蛋白水平都较低,但尽管存在明显的缺铁情况,血浆铁蛋白水平仍可能处于正常范围。相比之下,转铁蛋白饱和度可用于确定骨髓铁供应不足。在这两个社会经济群体中,1岁以下婴儿缺铁的频率相似。然而,在1至2岁之间,接受定期监测的儿童未检测到缺铁情况,但所有处于社会不利地位的婴儿都出现了缺铁,这表明需要定期补充铁剂。

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