Trevisan G, Cattin L, Ponte E, Velari R, Feoli E
Biochem Exp Biol. 1979;15(3):211-5.
Ninety-nine diabetics were simultaneously given a capillaroscopic examination of periungual walls and an electrocardiogram evaluated according to the Minnesota Code. From these tests the following data were recorded: a. the number of knobs revealed by capillaroscopy is inferior, in a statistically significant manner, in groups having "major abnormalities"; b. capillaroscopic abnormalities did not seem to be definitely correlated to age, but rather to the length of time diabetes mellitus was present; in particular, these abnormalities were quite evident in subjects diagnosed as diabetics for the first time. This procedure is therefore extremely useful for the early diagnosis of diabetic microangiopathy; c. electrocardiographic abnormalities are correlated to patient's age, whereas are not related to the period of the illness. Although the small sampling obliges us to maintain certain reservations, such abnormalities were more frequent in subjects taking antidiabetic drugs orally.
对99名糖尿病患者同时进行了甲周壁毛细血管镜检查，并根据明尼苏达编码对心电图进行了评估。从这些检查中记录了以下数据：a. 在有“严重异常”的组中，毛细血管镜检查发现的小结数量在统计学上显著较少；b. 毛细血管镜异常似乎与年龄没有明确关联，而与糖尿病病程长短有关；特别是，这些异常在首次被诊断为糖尿病的患者中非常明显。因此，该检查方法对糖尿病微血管病变的早期诊断极为有用；c. 心电图异常与患者年龄相关，而与病程无关。尽管样本量小使我们不得不有所保留，但口服降糖药的患者中此类异常更为常见。
