轻度水合氯醛和戊巴比妥麻醉对犬动脉血酸碱状态及氧合的影响。
The effect of light chloralose and pentobarbitone anaesthesia on the acid-base state and oxygenation of arterial blood in dogs.
作者信息
Ledsome J R, Linden R J, Norman J
出版信息
J Physiol. 1971 Feb;212(3):611-27. doi: 10.1113/jphysiol.1971.sp009345.
Abstract
- The effects of light anaesthesia of approximately 8 hr duration using either pentobarbitone or chloralose on the acid-base balance and oxygenation of arterial blood were determined in dogs breathing spontaneously.2. With pentobarbitone anaesthesia there was a slight initial respiratory acidaemia.3. With chloralose there was a non-respiratory acidaemia which was probably the result of using an unbuffered solvent.4. Changes in the acid-base balance and the oxygen concentration of the arterial blood over the course of each experiment were minimal.5. In one animal a pH of 7.07 was recorded; in others the oxygen tension on occasion was between 50 and 60 mm Hg. The value of monitoring the acid-base state and the oxygenation of blood in experimental preparations is discussed.
摘要
在自主呼吸的犬中，测定了使用戊巴比妥或氯醛糖进行约8小时浅麻醉对动脉血酸碱平衡和氧合的影响。
使用戊巴比妥麻醉时，最初有轻微的呼吸性酸血症。
使用氯醛糖时，存在非呼吸性酸血症，这可能是使用无缓冲溶剂的结果。
每个实验过程中动脉血酸碱平衡和氧浓度的变化极小。
在一只动物中记录到pH值为7.07；在其他动物中，氧分压有时在50至60毫米汞柱之间。讨论了在实验制剂中监测血液酸碱状态和氧合的价值。
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