Haugen A, Matre R
Cancer Lett. 1979 Dec;8(2):97-102. doi: 10.1016/0304-3835(79)90001-6.
Fetal rat brain cells, undergoing neoplastic transformation in long-term culture after a single transplacental pulse of N-ethyl-N-nitrosourea on the 18th day of gestation, were investigated for Fc gamma receptors. Rosette assay with cells in suspension and the hemadsorption to cells on coverglasses were used for their detection. The receptors were found on cells after about 2 months in culture. A maximum of 20% of the cells were Fc gamma receptor-positive after 3 months. About 3 weeks later no Fc gamma receptors could be detected. Malignant rat neurogenic cell lines were also negative.
对妊娠第18天经单次经胎盘给予N-乙基-N-亚硝基脲后在长期培养中发生肿瘤转化的胎鼠脑细胞进行了Fcγ受体研究。采用悬浮细胞玫瑰花结试验和盖玻片上细胞的血细胞吸附试验进行检测。培养约2个月后在细胞上发现了这些受体。3个月后，最多20%的细胞为Fcγ受体阳性。约3周后未检测到Fcγ受体。恶性大鼠神经源性细胞系也为阴性。
