内源性抑郁症患者的24小时血浆色氨酸水平（作者译）
[24 hours plasma tryptophan levels in patients with endogenous depression (author's transl)].
作者信息
Malatino L S, Calandra C, Costa M, Bongiorno G, Petrone G, Fiore C E
出版信息
Riv Patol Nerv Ment. 1979 Nov-Dec;100(6):340-6.
PMID:556121
Abstract
The variations of total and free tryptophan during 24 hours were measured in patients with endogenous depression. In depressive patients, plasma tryptophan levels are significantly lower than in control subjects. Plasma tryptophan levels in depressive patients are low during the night (when high at the same hours in normal subjects). The physiopathological mechanisms of such alterations and their possible influence on symptomathology are described.
摘要
对内源性抑郁症患者24小时内总色氨酸和游离色氨酸的变化进行了测量。在抑郁症患者中，血浆色氨酸水平显著低于对照组。抑郁症患者夜间血浆色氨酸水平较低（而正常受试者在相同时间该水平较高）。描述了这种改变的生理病理机制及其对症状学可能产生的影响。
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