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噻吗洛尔和二氯苯磺胺对无晶状体角膜移植术后眼压升高的影响。

Effects of timolol and Daranide on elevated intraocular pressure after aphakic keratoplasty.

作者信息

Olson R J, Kaufman H E, Zimmerman T J

出版信息

Ann Ophthalmol. 1979 Dec;11(12):1833-6.

PMID:556137
Abstract

In a randomized, blind clinical study, we tested the effect of timolol and Daranide against placebo medications among patients who had intraocular pressures greater than 30 mm Hg on the first postoperative day after aphakic keratoplasty. The study failed to show any significant difference in the pressure course. We concluded that because this type of severe secondary glaucoma is extremely difficult to treat, it should be prevented by using a donor cornea larger in size than the recipient bed.

摘要

在一项随机、盲法临床研究中,我们对无晶状体角膜移植术后第一天眼压高于30 mmHg的患者,测试了噻吗洛尔和二氯苯磺胺相对于安慰剂药物的效果。该研究未能显示出眼压变化过程中的任何显著差异。我们得出结论,鉴于这种类型的严重继发性青光眼极难治疗,应使用比受体床更大尺寸的供体角膜来预防。

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1
Effects of timolol and Daranide on elevated intraocular pressure after aphakic keratoplasty.噻吗洛尔和二氯苯磺胺对无晶状体角膜移植术后眼压升高的影响。
Ann Ophthalmol. 1979 Dec;11(12):1833-6.
2
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[Timolol in simple glaucoma: action after one instillation of the drug (author's transl)].
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Effect of timolol therapy on outflow facility.
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Intraocular pressure elevation within the first 24 hours after cataract surgery in patients with glaucoma or exfoliation syndrome.青光眼或剥脱综合征患者白内障手术后24小时内眼压升高。
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