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鼻腔和支气管激发试验中含甘油稀释剂引起的非特异性反应。

Non-specific reactions caused by diluents containing glycerol in nasal and bronchial challenge tests.

作者信息

Haahtela T, Lahdensuo A

出版信息

Clin Allergy. 1979 May;9(3):225-7. doi: 10.1111/j.1365-2222.1979.tb01546.x.

DOI:10.1111/j.1365-2222.1979.tb01546.x
PMID:556187
Abstract

Sixty-one patients hospitalized because of asthma and/or allergic rhinitis were given nasal and bronchial challenge tests with diluents containing glycerol. 62% of the patients with rhinitis and 37% of those with asthma gave positive reactions. Glycerol should therefore not be used in allergen extracts which are meant for challenge tests. The non-specific effect of glycerol seems to be cumulative with increasing dose.

摘要

61名因哮喘和/或过敏性鼻炎住院的患者接受了含甘油稀释剂的鼻腔和支气管激发试验。鼻炎患者中有62%、哮喘患者中有37%出现阳性反应。因此,甘油不应使用于用于激发试验的变应原提取物中。甘油的非特异性作用似乎随着剂量增加而累积。

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