慢性己酮可可碱治疗对间歇性跛行患者运动耐力和血流动力学参数的影响（作者译）
[The influence of chronic pentroxifylline medication on ergometric and hemodynamic parameters in intermittent claudication (author's transl)].
作者信息
Rudofsky G, Brock F E, Ulrich M, Nobbe F
出版信息
Med Klin. 1979 Jul 13;74(28-29):1093-6.
PMID:556192
Abstract
In an open clinical trial 14 patients with intermittent claudication caused by an obliteration of the femoral artery received 400 mg pentoxifylline 3 times daily over a period of 6 months. The walking distance, time to peak flow and calf ergometry showed a significant increase. Minor improvement of working hyperemia and peak flow could be found. The systolic pressure gradient over the obstruction didn't change. No patient complained about side effects.
摘要
在一项开放性临床试验中，14例因股动脉闭塞导致间歇性跛行的患者，在6个月的时间里每日3次接受400毫克己酮可可碱治疗。步行距离、达到峰值血流的时间和小腿测力计检查结果显示有显著增加。工作性充血和峰值血流有轻微改善。阻塞部位的收缩压梯度没有变化。没有患者抱怨有副作用。
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