Munari C, Modesto S, Matteuzzi G, Pacifico L
Rev Electroencephalogr Neurophysiol Clin. 1977 Apr-Jun;7(2):198-9. doi: 10.1016/s0370-4475(77)80081-6.
7 patients (aged 15 months-72 years) were treated by intravenous infusion of alfatesine in varying dose depending on age and body weight. Treatment was effective in 6 of the 7 patients, 4 of whom had previously derived no benefit from standard treatment with benzodiazepines. Intravenous injection in 2 cases only increased the interval between seizures from 3-12 minutes to 25-40 minutes. No major side-effects were observed.
7名患者(年龄在15个月至72岁之间)接受了阿法替辛静脉输注治疗,剂量根据年龄和体重有所不同。7名患者中有6名治疗有效,其中4名患者此前接受苯二氮䓬类标准治疗无效。仅2例静脉注射后癫痫发作间隔时间从3 - 12分钟延长至25 - 40分钟。未观察到重大副作用。