体内一种可扩散因子对粒细胞生成的刺激作用。
STimulation of granulocytopoiesis by a diffusible factor in vivo.
作者信息
Rothstein G, Hügl E H, Bishop C R, Athens J W, Ashenbrucker H E
出版信息
J Clin Invest. 1971 Sep;50(9):2004-7. doi: 10.1172/JCI106693.
Abstract
A millipore diffusion chamber system was used to cultivate mouse marrow in the abdomens of irradiated and unirradiated host mice for 24 hr. When the irradiated hosts were 72, 96, or 120 hr postirradiation, the number of blasts and promyelocytes in the implanted chambers after cultivation was greater than those in the same marrow cultivated in unirradiated hosts. These data indicate that in vivo, there is stimulation of granulocytopoiesis by a diffusible factor or factors.
摘要
采用微孔扩散室系统，将小鼠骨髓在经照射和未经照射的宿主小鼠腹部培养24小时。当照射后的宿主处于照射后72、96或120小时时，培养后植入室中的母细胞和早幼粒细胞数量多于在未经照射的宿主中培养的相同骨髓中的细胞数量。这些数据表明，在体内，存在一种或多种可扩散因子对粒细胞生成的刺激作用。
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