Shift in binocular disparity causes compensatory change in the cortical structure of kittens.

Kittens were raised with prisms in front of their eyes which introduced a vertical disparity. At 4 months of age the disparity necessary to maximally stimulate a sample of binocular cortical cells was determined. The distribution of optimal disparities was abnormal, and shifted in a direction which would tend to compensate for the prism-induced disparity.