自主通气与控制通气对犬肺泡氟烷浓度上升速率的影响。

The effect of spontaneous versus controlled ventilation on the rate of rise of alveolar halothane concentration in dogs.

作者信息

Gibbons R T, Steffey E P, Eger E I

出版信息

Anesth Analg. 1977 Jan-Feb;56(1):32-4. doi: 10.1213/00000539-197701000-00010.

DOI:10.1213/00000539-197701000-00010

Abstract

The rate of rise of the alveolar:inspired halothane concentration (F delta/F1) ratio was measured in dogs breathing spontaneously. These rates were measured at inspired concentrations of 0.3, 1.5, and 4 percent. Initially, FON (FA/F1) ratio was measured in dogs breathing spontaneously. These rates were measured at inspired concentrations of 0.3, 1.5, and 4 percent. Initially FA/F1 rose at similar rates for all 3 concentrations, but a 4 percent, the plateau attained was lower as a result of respiratory depression. In a 2nd group of dogs, FA/FI was measured for inspired concentrations of 0.3, 1.5, 4, and 6 percent during controlled ventilation. FA/FI rose at similar rates at the lower 2 concentrations but at progressively more rapid rates at inspired concentrations of 4 and 6 percent, presumably as a result of circulatory depression.

摘要

在自主呼吸的犬中测量肺泡内氟烷浓度与吸入氟烷浓度之比（Fδ/F1）的上升速率。这些速率是在吸入浓度为0.3%、1.5%和4%时测量的。最初，在自主呼吸的犬中测量FON（FA/F1）比值。这些速率是在吸入浓度为0.3%、1.5%和4%时测量的。最初，对于所有3种浓度，FA/F1以相似的速率上升，但在4%时，由于呼吸抑制，达到的平台期较低。在第二组犬中，在控制通气期间测量吸入浓度为0.3%、1.5%、4%和6%时的FA/FI。在较低的2种浓度下，FA/FI以相似的速率上升，但在吸入浓度为4%和6%时，上升速率逐渐加快，这可能是由于循环抑制所致。