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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

J Physiol. 1971 Aug;217(1):243-57. doi: 10.1113/jphysiol.1971.sp009569.

A study has been made of the T-system and sarcoplasmic reticulum (SR) in slow muscle fibres of the frog, Rana temporaria.2. The size of the T-system was measured by an autoradiographic method, using tritium-labelled albumin as a marker. Its volume, expressed as a fraction of that of the fibre, was found to be 1.8 x 10(-3), as compared with a figure of 3.9 x 10(-3) for the T-system in a twitch fibre.3. The spatial distribution of the T-tubules, and their association with the SR, was studied with the electron microscope, employing ferritin and the enzyme peroxidase as markers. The observations show (a) the tubules form a three dimensional, rather than transverse, network and (b) the area of triadic (and diadic) contact with the SR is 5-10 x smaller than in a twitch fibre.4. The possibility that the T-system and SR of the slow fibre participate in linking membrane excitation with contraction is discussed in the light of these findings.

对林蛙慢肌纤维中的T管系统和肌浆网（SR）进行了一项研究。
通过放射自显影法，以氚标记的白蛋白作为标志物来测量T管系统的大小。其体积以纤维体积的分数表示，结果发现为1.8×10⁻³，而抽动纤维中T管系统的这一数值为3.9×10⁻³。
利用铁蛋白和过氧化物酶作为标志物，通过电子显微镜研究了T小管的空间分布及其与肌浆网的关联。观察结果表明：（a）小管形成三维网络而非横向网络；（b）与肌浆网三联体（和二联体）接触的面积比抽动纤维中的小5至10倍。
根据这些发现，讨论了慢肌纤维的T管系统和肌浆网参与将膜兴奋与收缩联系起来的可能性。

J Physiol. 1971 Aug;217(1):243-57. doi: 10.1113/jphysiol.1971.sp009569.

A study has been made of the T-system and sarcoplasmic reticulum (SR) in slow muscle fibres of the frog, Rana temporaria.2. The size of the T-system was measured by an autoradiographic method, using tritium-labelled albumin as a marker. Its volume, expressed as a fraction of that of the fibre, was found to be 1.8 x 10(-3), as compared with a figure of 3.9 x 10(-3) for the T-system in a twitch fibre.3. The spatial distribution of the T-tubules, and their association with the SR, was studied with the electron microscope, employing ferritin and the enzyme peroxidase as markers. The observations show (a) the tubules form a three dimensional, rather than transverse, network and (b) the area of triadic (and diadic) contact with the SR is 5-10 x smaller than in a twitch fibre.4. The possibility that the T-system and SR of the slow fibre participate in linking membrane excitation with contraction is discussed in the light of these findings.

对林蛙慢肌纤维中的T管系统和肌浆网（SR）进行了一项研究。
通过放射自显影法，以氚标记的白蛋白作为标志物来测量T管系统的大小。其体积以纤维体积的分数表示，结果发现为1.8×10⁻³，而抽动纤维中T管系统的这一数值为3.9×10⁻³。
利用铁蛋白和过氧化物酶作为标志物，通过电子显微镜研究了T小管的空间分布及其与肌浆网的关联。观察结果表明：（a）小管形成三维网络而非横向网络；（b）与肌浆网三联体（和二联体）接触的面积比抽动纤维中的小5至10倍。
根据这些发现，讨论了慢肌纤维的T管系统和肌浆网参与将膜兴奋与收缩联系起来的可能性。