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儿童心内膜弹力纤维增生症,特别提及心脏神经节的病变

Endocardial fibroelastosis in children with special reference to the lesions of cardiac ganglia.

作者信息

Zóltowska A

出版信息

J Clin Pathol. 1971 Apr;24(3):263-9. doi: 10.1136/jcp.24.3.263.

DOI:10.1136/jcp.24.3.263
PMID:5573440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476966/
Abstract

In all cases of primary endocardial fibroelastosis investigated diffuse degenerative changes in the ganglion cells were detected. Thickened endocardium was formed by the proliferation of mesenchymal cells located under the endothelial endocardium and of the mesenchyme surrounding the necrobiotic muscle cells. In some cases ;axial' vacuolar degeneration, necrobiosis, and necrosis of muscle cells, interstitial oedema, and dilatation of capillaries and lymphatic spaces were found in the whole myocardium. In all cases these changes were in the subendocardial layer.In the cases discussed morphological changes in the endocardium were seen to be secondary to lesions in myocardial and possibly in neural structures.

摘要

在所有原发性心内膜弹力纤维增生症病例中,均检测到神经节细胞弥漫性退行性改变。增厚的心内膜由位于内皮心内膜下方的间充质细胞以及围绕坏死肌细胞的间充质增生形成。在某些病例中,整个心肌出现“轴向”空泡变性、坏死、肌细胞坏死、间质水肿以及毛细血管和淋巴管扩张。所有病例中,这些改变均见于心内膜下层。在所讨论的病例中,心内膜的形态学改变被认为是心肌及可能的神经结构病变的继发表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/74b2b6969c73/jclinpath00092-0083-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/19754ac695aa/jclinpath00092-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/013470ee136b/jclinpath00092-0079-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/d0cef20b924d/jclinpath00092-0079-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/78304606699a/jclinpath00092-0079-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/3d5322149ac6/jclinpath00092-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/f60bc29949b5/jclinpath00092-0080-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/96b278fbc806/jclinpath00092-0080-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/e222856d3dca/jclinpath00092-0080-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/a008a97b37d5/jclinpath00092-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/b7d2ec10d9b2/jclinpath00092-0081-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/38be095a059c/jclinpath00092-0081-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/427af2b0e4fa/jclinpath00092-0081-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/114e6c9dd6ee/jclinpath00092-0082-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d299/476966/74b2b6969c73/jclinpath00092-0083-a.jpg

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Congenital endocardial fibro-elastosis. II. A clinical and pathologic investigation of those cases without associated cardiac malformations including report of two familial instances.先天性心内膜弹力纤维增生症。II. 对无相关心脏畸形病例的临床与病理研究,包括两例家族性病例报告
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