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嘌呤对盘基网柄菌β-葡萄糖苷酶的抑制作用。

Inhibition of Dictyostelium discoideum beta-glucosidase by purines.

作者信息

Parish R W

出版信息

J Bacteriol. 1977 Mar;129(3):1642-4. doi: 10.1128/jb.129.3.1642-1644.1977.

Abstract

beta-Glucosidase of Dictyostelium discoideum is inhibited by purines in the following order: adenine greater than adenosine greater than 6-methylaminopurine greater than hypoxanthine greater than inosine greater than purine greater than guanosine. Adenine inhibits activity by 50% at 1 to 2 mM. The kinetics are complex because the enzyme is stimulated by substrate and inhibited by glucose.

摘要

盘基网柄菌的β-葡萄糖苷酶被嘌呤按以下顺序抑制:腺嘌呤>腺苷>6-甲基氨基嘌呤>次黄嘌呤>肌苷>嘌呤>鸟苷。腺嘌呤在1至2 mM时可抑制活性50%。动力学较为复杂,因为该酶受底物刺激且受葡萄糖抑制。

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