[The immunological characterization and isoelectric focusing of water-soluble proteins in the lens related to aging (author's transl)].

Immunelectrophoresis, antigen/antibody crossed electrophoresis and isoelectric focusing are applied to characterize lens crystallins. Using isoelectric focusing alpha-, beta- and gamma-crystallins are determined in bovine lens nucleus and equator. The data obtained are compared with those of rat and human lenses. In these three species a disappearance of specific beta- and gamma-crystallin components is observed depending on age. Further, the presence of crystallins is demonstrated in cornea and vitreous body.