Goto K, Millecchia L L, Westfall D P, Fleming W W
Pflugers Arch. 1977 Apr 25;368(3):253-61. doi: 10.1007/BF00585204.
Microelectrodes were used to compare a variety of electrophysiological parameters of the rat and guinea-pig vas deferens. In comparison to the guinea pig, spontaneous junction potentials in the rat tissue were of shorter duration and occurred with greater frequency and amplitude. Action potentials induced by nerve stimulation could be observed in the smooth muscle of both species. However, in the rat tissue the majority of action potentials were generated in the impaled cell while 60% of the action potentials in the guinea-pig vas deferens were propagated. When current was intracellularly applied, spike potentials could be induced in approximately 90% of the cells of the rat vas deferens but in less than 10% of the cells of the guinea-pig vas deferens. The space constant was 1.48 mm for the guinea-pig vas deferens, but less than 0.5 mm for the rat vas deferens. Electromicroscopic examination of the homologous tissues indicates that the differences in electrical properties can be accounted for in part by differences in morphology. The incidence and intimacy of neuromuscular contacts was greater in the rat vas deferens while the incidence of nexuses between smooth muscle cells was greater in the guinea-pig tissue.
使用微电极比较大鼠和豚鼠输精管的各种电生理参数。与豚鼠相比，大鼠组织中的自发连接电位持续时间较短，频率和幅度更高。两种动物的平滑肌中均可观察到神经刺激诱导的动作电位。然而，在大鼠组织中，大多数动作电位在刺入的细胞中产生，而豚鼠输精管中60%的动作电位是可传播的。当进行细胞内电流刺激时，约90%的大鼠输精管细胞可诱导出锋电位，而豚鼠输精管细胞中不到10%的细胞可诱导出锋电位。豚鼠输精管的空间常数为1.48毫米，而大鼠输精管的空间常数小于0.5毫米。对同源组织的电镜检查表明，电特性的差异部分可由形态学差异来解释。大鼠输精管中神经肌肉接触的发生率和紧密程度更高，而豚鼠组织中平滑肌细胞之间连接的发生率更高。
