Malavasi A, Ganau A, Serra G, Cassisa L, Piga G, Rappelli A
Arch Sci Med (Torino). 1977 Apr-Jun;134(2):179-84.
The standardized mean protodiastolic speed of the posterior wall (Vpwd), non standardized speed (DEV) and maximum speed (DEVM) obtained with ultrasounds, are capable of distinguishing subjects with hypertrophic subaortic stenosis (IHSS), in whom there is a diminution in compliance, from normal subjects. As this compliance diminution is liable to limit fibrocell lengthening to the extent of its distension speed, the Vpwd has been used in the plotting of ventricular function curves in replacement of telediastolic volume (as an expression of fibre lengthening). An excellent correlation was found between Vpwd and mean speed of circumferential shortening of the fibre (Mvcf) and the ejection fraction (EF) used as indices of cardiac work. The comparison shows that the two groups lie on the same curve of ventricular function and that subjects with IHSS operate low down owing to the brevity of their sarcomeres. The Vpwd can thus be utilized as an indirect index of fibre length and in the plotting of left ventricular function curves.
通过超声获得的后壁标准化平均舒张前期速度(Vpwd)、非标准化速度(DEV)和最大速度(DEVM),能够区分肥厚性主动脉瓣下狭窄(IHSS)患者和正常受试者,IHSS患者的顺应性降低。由于这种顺应性降低易于将纤维细胞的伸长限制在其扩张速度的范围内,Vpwd已被用于绘制心室功能曲线,以替代舒张末期容积(作为纤维伸长的一种表达)。发现Vpwd与用作心脏工作指标的纤维圆周缩短平均速度(Mvcf)和射血分数(EF)之间存在极好的相关性。比较表明,两组位于同一条心室功能曲线上,并且IHSS患者由于其肌节较短而处于较低位置。因此,Vpwd可作为纤维长度的间接指标,并用于绘制左心室功能曲线。