Thomas G J, Prescott B, Olins D E
Science. 1977 Jul 22;197(4301):385-8. doi: 10.1126/science.560060.
Laser Raman spectroscopy indicates that the inner histones which are bound to DNA in chromatin or in isolated nu bodies are similar in conformation to the inner histones which are dissociated from DNA in high-salt solutions. This structure contains, on the average, 51+/-5% alpha-helix and no substantial beta-sheet conformation. It is proposed that the protein core of the nu body has a high alpha-helix content.
激光拉曼光谱表明，在染色质或分离的核小体中与DNA结合的内部组蛋白，其构象与在高盐溶液中从DNA上解离的内部组蛋白相似。这种结构平均含有51±5%的α-螺旋，且没有大量的β-折叠构象。有人提出，核小体的蛋白质核心具有较高的α-螺旋含量。
