Pathological findings in three cases of fungal endocarditis complicating open-heart surgery.

Three cases of fungal endocarditis are described, each following a homograft valve replacement for aortic stenosis. The causative organism was C. albicans. The characteristic findings included soft, easily detached vegetations consisting of fungal colonies, aneurysms, embolization of large vessels, and lack of response to current therapeutic measures. The source of the infection is obscure.