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[24小时内不同时间健康人肾上腺、交感-肾上腺系统激素活性指标及血液动力学的变化]

[Changes in the indicators of hormonal activity of the adrenal glands, sympathetic-adrenal system and hemodynamics in healthy persons at different times during the 24-hour period].

作者信息

Shurygin D Ia, Alekseeva N M, Karlov V A, Chireĭkin L V, Iakovlev V A

出版信息

Probl Endokrinol (Mosk). 1977 May-Jun;23(3):50-7.

PMID:560695
Abstract

The following were studied in 24 healthy men aged from 20 to 40 years: circadian rhythm of catecholamines and their precursors production, 17-ketosteroids, 17-oxycorticosteroids, variational pulsometry indices, arterial pressure parameters, resilient-viscous properties of large arterial vessels and arterioles, indices characterizing the mechanical activity of the myocardium. Comparison of the results obtained indicated that, although there existed no complete correlation between these indices, there proved to be a nocturnal tendency to reduction of noradrenaline and dopamine production, to reduction of 17-ketosteroids and 17-oxycorticosteroids, along with rarefaction of cardiac contractions, increased variation in the rhythm, and diminution of arterial pressure and cardiac output parameters. Reverse changes were noted during the day-time.

摘要

对24名年龄在20至40岁的健康男性进行了以下研究:儿茶酚胺及其前体生成的昼夜节律、17-酮类固醇、17-氧皮质类固醇、变分脉搏测量指数、动脉压参数、大动脉血管和小动脉的弹性粘性特性、表征心肌机械活动的指数。对所得结果的比较表明,尽管这些指数之间不存在完全相关性,但事实证明,夜间去甲肾上腺素和多巴胺生成减少、17-酮类固醇和17-氧皮质类固醇减少,同时心脏收缩稀疏、节律变化增加、动脉压和心输出量参数减小。白天则出现相反的变化。

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